ふじい　ひでき

藤猪　英樹

Hideki FUJII
医学部
所員
  • 分野 :
    生物学
  • TEL :
    045-566-1328
  • 専門 :
    免疫学，微生物学
  • 学歴 :
    北海道大学大学院理学研究科博士課程修了（博士（理学））
  • 所属学会 :
    細菌学会（評議員），免疫学会，ウイルス学会，化学療法学会，HTLV学会
  • 担当教科 :
    医学部生物学I，医学部生物学実験

研究・教育

（テーマ）

・ファージ療法の開発・抗菌薬抵抗性メカニズムの解明・感染免疫のダイナミクスに関する研究

主要論文

  1. Putra Wigianto AY, Ishida Y, Iwawaki Y, Goto T, Watanabe M, Sekine K, Hamada K, Murakami K, Fujii H, Ichikawa T. (2022) 2-methacryloyloxyethyl phosphorylcholine polymer treatment prevents Candida albicans biofilm formation on acrylic resin. J Prosthodont ResD_22_00102 doi

  2. Uemura Y, Hiroshima Y, Tada A, Murakami K, Yoshida K, Inagaki Y, Kuwahara T, Murakami A, Fujii H, Yumoto H. (2022) Porphyromonas gingivalis Outer Membrane Vesicles Stimulate Gingival Epithelial Cells to Induce Pro-Inflammatory Cytokines via the MAPK and STING Pathways. Biomedicines10(10):2643 doi

  3. Okada N, Murakami A, Sato M, Nakamura S, Fujii S, Sogabe K, Takahashi M, Okada A, Abe A, Fujii H, Abe M, Azuma M, Ishizawa K. (2022) First reported case of Lachnoanaerobaculum gingivalis bacteremia in an acute myeloid leukemia patient with oral mucositis during high dose chemotherapy. Anaerobe76:102610 doi

  4. Pahlevi MR, Murakami K, Hiroshima Y, Murakami A, Fujii H. (2022) pruR and PA0065 Genes Are Responsible for Decreasing Antibiotic Tolerance by Autoinducer Analog-1 (AIA-1) in Pseudomonas aeruginosa. Antibiotics11(6):773 doi

  5. Nomura H, Wada N, Takahashi H, Kase Y, Yamagami J, Egami S, Iriki H, Mukai M, Kamata A, Ito H, Fujii H, Ishikura T, Koseki H, Watanabe T, Yamada T, Ohara O, Koyasu S, Amagai M. (2022) IgM to IgG class-switching is a necessary step for pemphigus phenotype induction in desmoglein 3-specific B cell receptor knock-in mouse. J Immunol208(3) 582-593 doi

  6. Abe N, Murakami K, Hiroshima Y, Amoh T, Sebe M, Kataoka K, Fujii H. (2022) Autoinducer analogs can provide bactericidal activity to macrolides in pseudomonas aeruginosa through antibiotic tolerance reduction. Antibiotics11(1):10 doi

  7. Azuma M, Murakami K, Murata R, Kataoka K, Fujii H, Miyake Y, Nishioka Y. (2020) Clinical Significance of Carbapenem-Tolerant Pseudomonas aeruginosa Isolated in the Respiratory Tract. Antibiotics9(9):626 doi

  8. Fujiwara N, Murakami K, Yoshida K, Sakurai S, Kudo Y, Ozaki K, Hirota K, Fujii H, Suzuki M, Miyake Y, Yumoto H. (2020) Suppressive effects of 2-methacryloyloxyethyl phosphorylcholine (MPC)-polymer on the adherence of Candida species and MRSA to acrylic denture resin. Heliyon6(6):e04211 doi

  9. Yumoto H, Hirota K, Hirao K, Ninomiya M, Murakami K, Fujii H, Miyake Y. (2019) The Pathogenic Factors from Oral Streptococci for Systemic Diseases. Int J Mol Sci 20(18):4571 doi

  10. Namkoong H, Ishii M, Fujii H, Asami T, Yagi K, Suzuki S, Azekawa S, Tasaka S, Hasegawa N, Betsuyaku T. (2019) Obesity worsens the outcome of influenza virus infection associated with impaired type I interferon induction in mice. Biochem Biophys Res Commun513(2):405-411 doi

  11. Namkoong H, Ishii M, Fujii H, Yagi K, Asami T, Asakura T, et al. (2018) Clarithromycin expands CD11b+Gr-1+ cells via the STAT3/Bv8 axis to ameliorate lethal endotoxic shock and post-influenza bacterial pneumonia. PLoS Pathog14(4):e1006955 doi

  12. Kunihiro M, Fujii H, Miyagi T, Takahashi Y, Tanaka R, Fukushima T, Ansari AA, Tanaka Y. (2016) Heat Shock Enhances the Expression of the Human T Cell Leukemia Virus Type-I (HTLV-I) Trans-Activator (Tax) Antigen in Human HTLV-I Infected Primary and Cultured T Cells. Viruses8(7):191 doi

  13. Yagi K, Ishii M, Namkoong H, Fujii H, Asami T, Suzuki S, Asakura T, Mizoguchi K, Kamo T, Tasaka S, Chiba N, Ubukata K, Iwata S, Kunkel SL, Hasegawa N, Betsuyaku T. (2016) Histone Deacetylase Inhibition Protects Mice against Lethal Post-Influenza Pneumococcal Infection. Crit Care Med44(10):e980-e987 doi

  14. Fujii H, Shimizu M, Miyagi T, Kunihiro M, Tanaka R, Takahashi Y, Tanaka Y. (2016) A potential of an anti-HTLV-1 gp46 neutralizing monoclonal antibody (LAT-27) for passive immunization against both horizontal and mother-to-child vertical infection with human T cell leukemia virus type-I. Viruses8(2):41 doi

  15. KurodaY, Maruyama K, Fujii H, Sugawara I, Ko S, Yasuda H, Matsui H, Matsuo K. (2016) Osteoprotegerin regulates pancreatic β-cell homeostasis upon microbial invasion. PLoS ONE11(1):e0146544 doi

メンバー

所員

物理学

電気電子工学

システムデザインマネジメント学

化学

生物学

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数学

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科学史

フランス語・フランス文学

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自然地理学

研究員/共同研究員/訪問学者

物理学

化学

生物学

数学

心理学

天文学

科学教育

人間科学

理科教育学

過去のメンバー一覧

Keio University Hiyoshi Campus

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