Ryohei FURUKAWA

Research Description

Immune system of the starfish

Selected Journal Publications

1. Yamazki, A., Morino, Y., Urata, M., Yamaguchi, M., Minokawa, T., Furukawa, R., Kondo, M., Wada, H.  (2020)  pmar1/phb homeobox genes and the evolution of the double-negative gate for endomesoderm specification in echinoderms.   Development  147. dev182139.  

   

2. Sekii, K., Yorimoto, S., Okamoto, H., Nagao, N., Maezawa, T., Matsui, Y., Yamaguchi, K., Furukawa, R., Shigenobu, S., Kobayashi, K.   (2019)  Transcriptomic analysis reveals differences in the regulation of amino acid metabolism in asexual and sexual planarians.  Sci Rep  9. 6132.  

   

3. 古川亮平  (2018)  マクロファージの起源  日本動物学会編 『動物学の百科事典』, 丸善出版  502-503  

   

4. Smith, LC., Arriza, V., Barela Hudgell, MA., Barone, G., Bodnar, AG., Buckley, KM., Cunsolo, V., Dheilly, N., Franchi, N., Fugmann, SD., Furukawa, R., Garcia-Arraras, J., enson, JH., Hibino, T., Irons, ZH., Li, C., Lun, CM., Majeske, AJ., Oren, M., Pagliara, P., Pinsino, A., Raftos, DA., Rast, JP., Samasa, B., Schillaci, D., Schrankel, CS., Stabili, L., Stensväg, K., Sutton, E.   (2018)  Echinodermata: The Complex Immune System in Echinoderms. In “Advances in Comparative Immunology”, EL Cooper, ed.   Springer Publisher  409-501 

   

5. Komaki, S., Shiwa, Y., Furukawa, R., Hachiya, T., Ohmomo, H., Otomo, R., Satoh, M., Hitomi, J., Sobue, K., Sasaki, M., Shimizu, A. (2018) iMETHYL: an integrative database of human DNA methylation, gene expression, and genomic variation. Human Genome Variation 5:18008

    

6. Komaki, S., Ohmomo, H., Hachiya, T., Furukawa, R., Shiwa, Y., Satoh, M., Endo, R., Doita, M., Sasaki, M., Shimizu, A. (2017) An epigenome-wide association study based on cell type-specific whole-genome bisulfite sequencing: Screening for DNA methylation signatures associated with bone mass. Integr Mol Med 4(5): 1-7

    

7. Saito, S., Hamanaka, G., Kawai, N., Furukawa, R., Gojobori, J., Tominaga, M., Kaneko, H. Satta, Y. (2017) Characterization of TRPA channels in the starfish Patiria pectinifera: involvement of thermally activated TRPA1 in thermotaxis in marine planktonic larvae. Sci Rep 7: 2173

    

8. Hachiya, T., Furukawa, R., Shiwa, Y., Ohmomo, H., Ono, K., Katsuoka, F., Nagasaki, M., Yasuda, J., Fuse, N., Kinoshita, K., Yamamoto, M., Tanno, K., Satoh, M., Endo, R., Sasaki, M., Sakata, K., Kobayashi, S., Ogasawara, K., Hitomi, J., Sobue, K., Shimizu, A. (2017) Genome-wide identification of inter-individually variable DNA methylation sites improves the efficacy of epigenetic association studies. npj Genomic Medicine 2: 11

    

9. Hachiya, T., Kamatani, Y., Takahashi, A., Hata, J., Furukawa, R., Shiwa, Y., Yamaji, T., Hara, M., Tanno, K., Ohmomo, H., Ono, K., Takashima, N., Matsuda, K., Wakai, K., Sawada, N., Iwasaki, M., Yamagishi, K., Ago, T., Ninomiya, T., Fukushima, A., Hozawa, A., Minegishi, N., Satoh, M., Endo, R., Sasaki, M., Sakata, K., Kobayashi, S., Ogasawara, K., Nakamura, M., Hitomi, J., Kita, Y., Tanaka, K., Iso, H., Kitazono, T., Kubo, M., Tanaka, H., Tsugane, S., Kiyohara, Y., Yamamoto, M., Sobue, K., Shimizu, A. (2017) Genetic Predisposition to Ischemic Stroke: A Polygenic Risk Score.  Stroke 48: 253-258

    

10. Furukawa, R., Hachiya T., Ohmomo H., Shiwa Y., Ono K., Suzuki S., Satoh M., Hitomi J., Sobue K. and Shimizu A.  (2016)  Intraindividual dynamics of transcriptome and genome-wide stability of DNA methylation.   Sci Rep  6. 26424 

    

11. Furukawa R., Tamaki K., Kaneko H. (2016) Two macrophage migration inhibitory factors regulate starfish larval immune cell chemotaxis. Immunol Cell Biol 94(4): 315-321

     

12. Shiwa Y., Hachiya T., Furukawa R., Ohmomo H., Ono K., Kudo H., Hata J., Hozawa A., Iwasaki M., Matsuda K., Minegishi N., Satoh M., Tanno K., Yamaji T., Wakai K., Hitomi J., Kiyohara Y., Kubo M., Tanaka H., Tsugane S., Yamamoto M., Sobue K., Shimizu A.  (2016)  Adjustment of cell-type composition minimizes systematic bias in blood DNA methylation profiles derived by DNA collection protocols.   PLoS ONE  11. e0147519 

    

13. 古川亮平, 清水厚志  (2016)  IMMオミックスレファレンスパネルの取り組み．  生化学   88: 36-43 

    

14. 大桃秀樹, 古川亮平, 清水厚志  (2016)  ヒト血液検体のトランスクリプトーム解析.   実験医学別冊 RNA-Seq実験ハンドブック　羊土社  74-82 (ISBN 978-4-7581-0194-3) 

    

15. 古川亮平, 八谷剛史, 清水厚志  (2016)  全エピゲノム関連解析（EWAS）.  金井弥栄編. 実験医学増刊 エピゲノム研究 修飾の全体像の理解から先制・個別化医療へ　羊土社,  76-82 (ISBN 978-4-7581-0355-8) 

    

16. Ohmomo, H., Hachiya, T., Shiwa, Y., Furukawa, R., Ono, K, Ito, S., Ishida, Y., Satoh, M., Hitomi, J., Sobue, K., Shimizu, A.  (2014)  Reduction of systematic bias in transcriptome data from human peripheral blood mononuclear cells for transportation and biobanking.   PLoS ONE  9. e104283 

    

17. Kawase, O., Furukawa, R.  (2014)  Regional difference of ray number variation in a starfish, Patiria pectinifera.  Annual Report of Premedical Sciences, Dokkyo Medical University  3: 49-52 

    

18. Furukawa, R., Funabashi, H., Matsumoto, M., Kaneko, H. (2012) Starfish ApDOCK protein essentially functions in larval defense system operated by mesenchyme cells. Immunol Cell Biol 90: 955-965

     

19. Furukawa, R., Matsumoto, M., Kaneko, H.  (2012) Characterization of a scavenger receptor cysteine-rich-domain-containing protein of the starfish, Asterina pectinifera: ApSRCR1 acts as an opsonin in the larval and adult innate immune systems.  Dev Comp Immunol 36(1): 51-61

     

20. 古川亮平　 (2009) ヒトデ幼生に探るマクロファージのご先祖② 自己と非自己をさかのぼって考える　 ミクロスコピア 26(2): 98-102

     

21. 古川亮平 (2009) ヒトデ幼生に探るマクロファージのご先祖① メチニコフの発見から１００年 ミクロスコピア 26(1): 9-16

     

22. Furukawa R., Takahashi Y., Nakajima Y., Dan-Sohkawa M. and Kaneko H.  (2009) Defense system by mesenchyme cells in bipinnaria larvae of the starfish, Asterina pectinifera. Dev Comp Immunol 33(2): 205-215